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              Recombinant protein products

              Name Mouse VEGFR3 / FLT-4 Protein/重組小鼠 VEGFR3 / FLT
              Specifications 20ug
              Serial number CZDB-008
              The price Inquiry
              Chinese name Mouse VEGFR3 / FLT-4 Protein/重組小鼠 VEGFR3 / FLT
              Molecular nickname Chy, Flt-4, VEGFR-3, VEGFR3
              Molecular species Mouse
              Express label His,S
              Express the host E. coli
              Concentration > 95 % as determined by SDS-PAGE
              Buffer Lyophilized from sterile PBS, pH 7.4
              Storage conditions -70°C,應避免反復凍融。
              Basic description Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.

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              鄂ICP備19022221號-2 Trigoats Co., Ltd.