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              Catalog peptides

              Name (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)
              Code [150234-52-9]
              The alias (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)
              Sequence (single letter abbreviation) SEVNLDAEF
              Sequence (three-letter abbreviation) H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-OH (trifluoroacetate salt)
              A basic description This peptide comprises a Cu2+-binding site. Binding of Cu2+ to the peptide induced oxidation of the cysteine and intermolecular dimerization of the peptide. The reduction of Cu2+ to Cu+ by Amyloid beta/A4 Protein Precursor may enhance the production of hydroxyl radicals which in turn may contribute to neurodegeneration in Alzheimer's disease.
              solubility
              The molecular weight 1023.1
              Chemical formula C44H66N10O18
              The purity 80%,90%,95%,98%,99%
              Weight 1mg,5mg,10mg,50mg,100mg,1g
              Storage conditions Store at -20°C. Keep tightly closed. Store in a cool dry place.
              Annotation
              Documents 文檔
              Figures 無圖片展示
              Reference M. Citron et al., Nature, 360, 672 (1992) M. Mullan et al., Nature Gen., 1, 345 (1992) S.R. Sahasrabudhe et al., J. Biol. Chem., 268, 16699 (1993)
              The C-terminal
              The N-terminal
              Chemical bridge

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